The girl group were performing at the Radio 1 Teen Awards at Wembley Arena and their former mentor Tulisa went along to show her support before their performance.
Tulisa – who wore a bright red mini-dress – was pictured backstage with her ‘Little Muffins’.
The Young singer was also there to represent The X Factor, and picked up the award for Best TV Show.
Then it was straight back to the studios for the second live show of the weekend, which saw judge Louis Walsh controversially send the sing-off to deadlock, which saved Rylan Clark but sent country singer Carolynne Poole packing.
Back at Wembley Arena, the Little Mix girls performed on stage to thousands of screaming fans, wearing sporty-style outfits.
But the girls missed out on any awards themselves, as all the music gongs – including best single, album and musical act – were picked up by their fellow X Factor stars One Direction.
Other famous faces at the event included Jacqueline Jossa, Taylor Swift, Kimberley Wyatt, Jorgie Porter, Reggie Yates, Misha B, and Olympians Ellie Simmonds, Laura Trott and Louis Smith.